Publications 2017-08-15T10:55:09+00:00


T cell population expansion in response to allogeneic cancer vaccine alone (DPV-001) or with granulocyte-macrophage colony-stimulating factor (GM-CSF) or imiquimod (I) for definitively-treated stage III NSCLC patients (pts)

Bernard A. Fox, Brian C. Boulmay, Rui Li, Kyle T Happel, Christopher Paustian, Tarsem Lal Moudgil, Sachin Puri, Christopher Dubay, Yoshinobu Koguchi, Adi Mehta, Fridtjof Lund-Johansen, Brenda K Fisher, William L Redmond, Carlo Bruno Bifulco, Augusto Ochoa, Hong-Ming Hu, Traci Hilton, Walter John Urba, Rachel E. Sanborn.

Journal of Clinical Oncology, 2017 (suppl; abstr e14639)

Ubiquitinated Proteins Isolated From Tumor Cells Are Efficient Substrates for Antigen Cross-Presentation

Yu G, Moudgil T, Cui Z, Mou Y, Wang L, Fox BA, Hu HM.

Journal of Immunotherapy, 2017 Jun;40(5):155-163. doi: 10.1097/CJI.0000000000000165..

Randomized PH II trial of allogeneic DPV-001 cancer vaccine alone or with adjuvant for curatively-treated stage III NSCLC

Rachel Sanborn, Brian Boulmay, Rui Li, Kyle Happel, Sachin Puri, Christopher Paustian, Christopher Dubay, Sandra Aung, Brenda Fisher, Carlo Bifulco, Keith Bahjat, Yoshinobu Koguchi, Augusto Ochoa, Hong-Ming Hu, Traci Hilton, Bernard Fox, Walter Urba

Journal of Thoracic Oncology, Volume 12, Issue S1, P2.02-043, January 2017 .

Combinational Immunotherapy with Allo-DRibble Vaccines and Anti-OX40 Co-Stimulation Leads to Generation of Cross-Reactive Effector T Cells and Tumor Regression

Yu G, Li Y, Cui Z, Morris NP, Weinberg AD, Fox BA, Urba WJ, Wang L, Hu HM.

Scientific Reports, 2016 Nov 22;6:37558. doi: 10.1038/srep37558.

Glimpse into the future: harnessing autophagy to promote anti-tumor immunity with the DRibbles vaccine

David Page, Tyler Hulett, Traci Hilton, Hong Ming Hu, Walter Urba, Bernard Fox

Journal of ImmunoTherapy of Cancer, Vol 4, Page 25, May 17, 2016

Preliminary analysis of immune responses in patients enrolled in a Phase II trial of cyclophosphamide with allogenic dribble vaccine alone (DPV-001) or with GM-CSF or imiquimod for adjuvant treatment of stage IIIa or IIIb NSCLC

Rachel Sanborn, Brian Boulmay, Rui Li, Bradley Spieler, Kyle Happel, Christopher Paustian, Tarsem Mougdil, Zipei Feng, Christopher Dubay, Brenda Fisher, Yoshinobu Koguchi, Sandra Aung, Eileen Mederos, Carlo Bifulco, Michael McNamara, Keith S Bahjat, William Redmond, Augusto C Ochoa, Hong Ming Hu, Bernard Fox, Walter Urba and Traci Hilton

Journal of ImmunoTherapy of Cancer, Vol 3, Suppl 2, November 4, 2015

Adoptive TIL in HPV-negative oral scca

Rom Leidner, Brendan D Curti, Roxanne M Payne, Walter Urba, Keith S Bahjat, Yoshinobu Koguchi, Krista Nelson, Jennifer A Moore, Marka Crittenden, Yedeh Ying, Ashish Patel, Allen Cheng, Tuan G Bui, Traci Hilton, Christopher Paustian, Sachin Puri, Hong Ming Hu, Carlo Bifulco, Zipei Feng, R Bryan Bell and Bernard Fox

Journal for ImmunoTherapy of Cancer, Vol 3, Suppl 2, November 4, 2015

Cross-presentation of viral antigens in DRibbles leads to efficient activation of virus-specific human memory T cells

Ye W, Xing Y, Paustian C, van de Ven R, Moudgil T, Hilton TL, Fox BA, Urba WJ, Zhao W, and Hu HM

Journal of Translational Medicine, April 16, 2014

OX40 is a potent immune-stimulating target in late stage cancer patients

Curti BD, Kovacsovics-Bankowski M, Morris N, Walker E, Chisholm L, Floyd K, Walker J, Gonzalez I, Meeuwsen T, Fox BA, Moudgil T, Miller W, Haley D, Coffey T, Fisher B, Delanty-Miller L, Rymarchyk N, Kelly T, Crocenzi T, Bernstein E, Sanborn R, Urba WJ, Weinberg AD.

Cancer Research, 2013 Dec 15;73(24):7189-7198. doi: 10.1158/0008-5472.CAN-12-4174. Epub 2013 Oct 31.

Autophagy-assisted antigen cross-presentation

Yongxiang Yi, Zhenxian Zhou, Su Shu, Yuan Fang, Chris Twitty, Traci L. Hilton, Sandra Aung, Walter J. Urba, Bernard A. Fox, Hong-Ming Hu, and Yuhuan Li

OncoImmunology, September 1, 2012

Tumor-Derived Autophagosome Vaccine: Mechanism of Cross-Presentation and Therapeutic Efficacy

Yuhuan Li, Li-Xin Wang, Puiyi Pang, Zhihua Cui, Sandra Aung, Daniel Haley, Bernard A. Fox, Walter J. Urba, and Hong-Ming Hu

Clinical Cancer Research, November 15, 2011

Tumor-Derived Autophagosome Vaccine: Induction of Cross-Protective Immune Responses against Short-lived Proteins through a p62-Dependent Mechanism

Christopher G. Twitty, Shawn M. Jensen, Hong-Ming Hu, and Bernard A. Fox

Clinical Cancer Research, October 15, 2011

Cross-presentation of tumor associated antigens through tumor-derived autophagosomes

Yuhuan Li, Li-xin Wang, Puiyi Pang, Chris Twitty, Bernard A. Fox, Sandra Aung, Walter J. Urba, and Hong-Ming Hu

Autophagy, May 6, 2009

Efficient Cross-presentation Depends on Autophagy in Tumor Cells

Yuhuan Li, Li-Xin Wang, Guojun Yang, Fang Hao, Walter J. Urba, and Hong-Ming Hu

Cancer Research, September 1, 2008